The NEW ERA of PANADOL and its types
What is Panadol?
What is the Classification of Panadol?
- Analgesic, non-narcotic
- Antipyretic
- Non-steroidal anti-inflammatory drug but due to its low degree of analgesic activity it is not consider in NSAID derivatives
Generic Name of Panadol:
What Products Come into the Market:
Structure of Panadol Paracetamol is same
There are more than 6 types of Panadol in the Market, So what is the difference between them?
1. Original Panadol 500 mg
This is the most common form of Panadol and the main ingredient is acetaminophen, which is the most commonly used painkiller ingredient in the world. This Panadol does not irritate the stomach and intestines when taken on an empty stomach and is suitable for most people.
2. Paracetamol Actifast
This Panadol is characterized by a relatively fast pain relief effect. Since this Panadol contains sodium (Sodium), there are 173mg of sodium in each painkiller tablet, it is not suitable for people with high blood pressure, or those who cannot eat foods high in sodium.
3. Panadol Extra
This Panadol has added caffeine to relieve migraines, and is suitable for people with migraine problems.
4. Panadol Extended
This Panadol is a high dose pain reliever so it can provide long-lasting pain relief.
5. Panadol Soluble
This Panadol is for people who are not good at swallowing pills.
6. Panadol Menstrual
This type of Panadol is indicated for women who suffer from menstrual pain. This Panadol has added Pamabrom to eliminate or reduce the water that accumulates in the body due to hormones and also to relieve the pain of cramps in the lower abdomen.
For the Consumer
Applies to acetaminophen: capsule, capsule liquid filled, elixir, liquid, powder, solution, suppository, suspension, tablet, tablet chewable, tablet disintegrating, tablet extended release
Other dosage forms:
- intravenous solution
Side effects requiring immediate medical attention
Along with its needed effects, acetaminophen (the active ingredient contained in Panadol) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking acetaminophen:
Rare
- Bloody or black, tarry stools
- bloody or cloudy urine
- fever with or without chills (not present before treatment and not caused by the condition being treated)
- pain in the lower back and/or side (severe and/or sharp)
- pinpoint red spots on the skin
- skin rash, hives, or itching
- sore throat (not present before treatment and not caused by the condition being treated)
- sores, ulcers, or white spots on the lips or in the mouth
- sudden decrease in the amount of urine
- unusual bleeding or bruising
- unusual tiredness or weakness
- yellow eyes or skin
Get emergency help immediately if any of the following symptoms of overdose occur while taking acetaminophen:
Symptoms of overdose
- Diarrhea
- increased sweating
- loss of appetite
- nausea or vomiting
- stomach cramps or pain
- swelling, pain, or tenderness in the upper abdomen or stomach area
For Healthcare Professionals
Applies to acetaminophen: compounding powder, intravenous solution, oral capsule, oral granule effervescent, oral liquid, oral powder, oral powder for reconstitution, oral suspension, oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet extended release, rectal suppository
General
In general, acetaminophen (the active ingredient contained in Panadol) is well-tolerated when administered in therapeutic doses. The most commonly reported adverse reactions have included nausea, vomiting, constipation. Injection site pain and injection site reaction have been reported with the IV product.
Hepatic
Common (1% to 10%): Increased aspartate aminotransferase
Rare (less than 0.1%): Increased hepatic transaminases
Frequency not reported: Liver failure
Gastrointestinal
Very common (10% or more): Nausea (up to 34%), Vomiting (up to 15%)
Common (1% to 10%): Abdominal pain, diarrhea, constipation, dyspepsia, enlarged abdomen
Frequency not reported: Dry mouth
Hypersensitivity
Postmarketing reports: Anaphylaxis, hypersensitivity reactions
Hematologic
Common (1% to 10%): Anemia, postoperative hemorrhage
Very rare (less than 0.01%): Thrombocytopenia, leucopenia, neutropenia
Dermatologic
Common (1% to 10%): Rash, pruritus
Rare (less than 0.1%): Serious skin reactions such as acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, and toxic epidermal necrolysis
Very rare (less than 0.01%): Pemphigoid reaction, pustular rash, Lyell syndrome
Respiratory
Common (1% to 10%): Dyspnea, abnormal breath sounds, pulmonary edema, hypoxia, pleural effusion, stridor, wheezing, coughing
Cardiovascular
Common (1% to 10%): Peripheral edema, hypertension, hypotension, tachycardia, chest pain
Metabolic
Common (1% to 10%): Hypokalemia, hyperglycemia
Nervous system
Common (1% to 10%): Headache, dizziness
Frequency not reported: Dystonia
Musculoskeletal
Common (1% to 10%): Muscle spasms, trismus
Psychiatric
Common (1% to 10%): Insomnia, anxiety
Genitourinary
Common (1% to 10%): Oliguria
Local
Common (1% to 10%): Infusion site pain, injection site reactions
Ocular
Common (1% to 10%): Periorbital edema
Other
Common (1% to 10%): Pyrexia, fatigue
Rare (0.01% to 0.1%): Malaise
References:
British National Formulary
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